Acrokeratosis paraneoplastica (Bazex syndrome): Report of a case associated with small cell lung carcinoma and review of the literature

Authors

  • Jessica Zarzour
  • Satinder Singh
  • Aleodor Andea
  • Jennifer Cafardi

DOI:

https://doi.org/10.3941/jrcr.v5i7.663

Keywords:

Acrokeratosis paraneoplastica, Bazex syndrome, paraneoplastic

Abstract

Acrokeratosis paraneoplastic (Bazex syndrome) is a rare, but distinctive paraneoplastic dermatosis characterized by erythematosquamous lesions located at the acral sites and is most commonly associated with carcinomas of the upper aerodigestive tract.  We report a 58-year-old female with a history of a pigmented rash on her extremities, thick keratotic plaques on her hands, and brittle nails.  Chest imaging revealed a right upper lobe mass that was proven to be small cell lung carcinoma.  While Bazex syndrome has been described in the dermatology literature, it is also important for the radiologist to be aware of this entity and its common presentations.

Author Biographies

Jessica Zarzour

Jessica Zarzour, MD

University of Alabama at Birmingham

Department of Radiology

619 19th Street South, Birmingham, AL 35294

jgzarzour@uabmc.edu

205-934-3166

 

Satinder Singh

Satinder Singh, MD, FCCP

Department of Radiology

619 19th Street South, Birmingham, AL 35294

ssingh@uabmc.edu

205-934-5345

Aleodor Andea

Aleodor Andea, MD

Department of Pathology

P220 West Pavilion

619 South 19th Street, Birmingham, AL 35233

aandea@uab.edu

205-975-6941

 

Jennifer Cafardi

Jennifer A. Cafardi, MD, FAAD

Department of Dermatology

EFH 414

1530 3rd Avenue South, Birmingham, AL 35294

jacafardi@uab.edu

205-934-5188

Published

2011-07-04

Issue

Section

General Radiology