Hepatic Endometriosis Mimicking Metastatic Disease: A Case Report and Review of the Literature

Abstract

Endometriosis of the liver is an uncommon disease characterized by the presence of endometrial tissue in the liver.  There are no pathognomonic radiological features for hepatic endometriosis and preoperative diagnosis is difficult by imaging.  Most cases are diagnosed after surgery.  We report atypical imaging features of hepatic endometriosis in a 61 year- old female that mimic metastatic disease to the liver.  She was referred to our institution with a presumed diagnosis of metastatic neuroendocrine tumors to the liver. After imaging guided core biopsy and histologic and immunohistochemical analysis, the diagnosis of hepatic endometrial stromal proliferation was made. We review the literature and provide imaging features that may help in reaching the correct diagnosis of hepatic endometriosis.