A Rare Case of Localized Malignant Pleural Mesothelioma Mimicking an Anterior Mediastinal Mass

Authors

  • Hong Wan Yap Department of Diagnostic Radiology, Singapore General Hospital, Singapore
  • Chun Yuen Chow Department of Anatomical Pathology, Singapore General Hospital, Singapore
  • Boon Hean Ong Department of Cardiothoracic Surgery, National Heart Centre, Singapore
  • Salahudeen Mohamed Haja Mohideen Department of Diagnostic Radiology, Singapore General Hospital, Singapore

DOI:

https://doi.org/10.3941/jrcr.5792

Abstract

Pleural mesotheliomas commonly present as diffuse nodular involvement of the affected pleural lining, whereas a localized form of pleural mesothelioma is rare. We report a rare and unusual case of localized pleural mesothelioma that initially mimicked an anterior mediastinal mass on radiographs and computed tomography with atypical features such as the lack of asbestos exposure history and pleural effusion, which prompted other differentials of anterior mediastinal masses during tumor board discussions. This case emphasizes the consideration of localized mesothelioma in the differential diagnosis of focal masses involving the mediastinal pleura.

AP Chest radiograph demonstrating a mass overlapping the left hilum suggestive of an anterior mediastinal mass (white arrow).

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Published

2025-08-30

Issue

Vol. 19 No. 8 (2025)

Section

Thoracic Radiology

License

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