A Rare Case of Acute Necrotizing Encephalopathy in A Young Adult: Correlation between Neuroradiological Imaging and Clinical Outcome

Authors

  • Davide Fabbricatore Departement of Translation Medicine, University of Eastern Piemonte UPO/SCDU Radiodiagnostica, Ospedale Maggiore Della Carità,
  • Marco Spinetta Departement of Translation Medicine, University of Eastern Piemonte UPO, Italy /SCDU Radiodiagnostica, Ospedale Maggiore Della Carità, Italy
  • Alessandro Carriero Departement of Translation Medicine, University of Eastern Piemonte UPO, Italy /SCDU Radiodiagnostica, Ospedale Maggiore Della Carità, Italy
  • Anna Colarieti Departement of Translation Medicine, University of Eastern Piemonte UPO, Italy /SCDU Radiodiagnostica, Ospedale Maggiore Della Carità, Italy

DOI:

https://doi.org/10.3941/jrcr.5755

Abstract

Acute necrotizing encephalopathy (ANE) is a rare, potentially fatal neurological disorder predominantly affecting pediatric patients, with a poor prognosis and high mortality rate. Here, we report a case of a 22-year-old woman diagnosed with ANE, analyzing neuroimaging features correlated with clinical outcomes. Brain magnetic resonance imaging demonstrated characteristic extensive bilateral symmetric lesions involving the thalamus, external capsule, optic tracts, and mammillary bodies. Following corticosteroid therapy, a follow-up MRI at three months revealed complete remission.

The non-contrast CT scan did not reveal any evident focal lesions in the brain tissue.

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Published

2025-12-30

Issue

Vol. 19 No. 12 (2025)

Section

Neuroradiology

License

Copyright (c) 2025 Journal of Radiology Case Reports

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