Neuroendocrine Prostate Cancer: Report of a Prostate Cancer Subtype with Atypical Metastatic Imaging and Clinical Findings

Authors

  • Bryan Nixon Department of Radiology, University of Miami, Miami, USA
  • Pritish Aher Department of Radiology, University of Miami, Miami, USA

DOI:

https://doi.org/10.3941/jrcr.5324

Abstract

Prostate cancer is the leading cause of malignancy in males, and the vast majority of cases consist of androgen-sensitive acinar adenocarcinoma. Multiple relatively rare subtypes of prostate malignancy have been described, including a neuroendocrine prostate cancer, which can arise in response to androgen-deprivation treatment in the setting of existing prostatic adenocarcinoma. Neuroendocrine prostate cancer is an uncommon subtype of prostatic cancer with a highly aggressive course and lack of distinguishing features on conventional imaging. We present a case of prostatic cancer which developed into neuroendocrine prostate cancer with atypical metastatic imaging appearance and describe characteristics that may suggest a histopathologic change from the original malignancy.

One month later, progression of metastatic disease is noted on imaging for other clinical indications

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Published

2024-05-31

Issue

Section

General Radiology