Rosai-Dorfman Disease in a Pediatric Patient: Imaging Findings and Pathology with a brief review of the Literature


  • Thomas Hartmann Medical Student, University of Central Florida College of Medicine, Orlando, USA
  • Nadia Solomon Department of Radiology and Biomedical Imaging, Yale New Haven Hospital, New Haven, USA
  • Gabriel Lerner Department of Pathology and Laboratory Medicine, Yale New Haven Hospital, New Haven, USA
  • Lauren Ehrlich Department of Radiology and Biomedical Imaging, Yale New Haven Hospital, New Haven, USA



Rosai-Dorfman Disease, Sinus histiocytosis with massive lymphadenopathy, inguinal, pediatric, magnetic resonance imaging, ultrasound


Rosai-Dorfman Disease, otherwise known as sinus histiocytosis with massive lymphadenopathy, is a rare form of non-Langerhans cell histiocytosis with an estimated incidence of 100 cases per year in the United States. Due to its variable presentation and nonspecific clinical findings, it is particularly difficult to diagnose in pediatric patients. We report a case of an 11-month-old male who presented with a 4-day history of a right groin mass. Ultrasound of the groin and pelvis demonstrated, and MRI of the abdomen and pelvis confirmed an inguinal mass with surrounding lymphadenopathy. Pathology confirmed Rosai-Dorfman Disease and the patient improved after starting oral steroid therapy. To the best of our knowledge, this is the first case of Rosai-Dorfman Disease involving the inguinal region in an infant under 1 year of age reported in the literature. In this case report, we discuss the imaging and histology findings as well as provide a brief literature review for this diagnosis.

11-month-old male with a palpable, reducible mass in the right inguinal region later diagnosed as Rosai-Dorfman Disease






Pediatric Radiology