Co-existent Epicardial Paraganglioma and Anterior Mediastinal Thymoma

Authors

  • Matthew G Dudgeon
  • Sushilkumar K Sonavane
  • Ephraim E Parent
  • Andras Khoor
  • Mathew Thomas

DOI:

https://doi.org/10.3941/jrcr.v14i10.4101

Keywords:

Cardiac, Epicardial, Paraganglioma, Mediastinal Mass, Thymoma, Hereditary, CT, MRI, Gallium-68 DOTA-TATE, PET-CT, Succinate dehydrogenase (SDH) subunits

Abstract

Thymoma and paraganglioma are known causes of mediastinal masses, the latter being extremely rare. Thymomas arise from remnant thymic tissue in the anterior mediastinum; whereas, thoracic paragangliomas arise from para-aortic or para-vertebral sympathetic chain ganglion (derivatives of embryonic neural crest) in the middle or posterior mediastinum. We report a case of a middle-aged woman with two mediastinal masses, originally believed to be a single tumor or primary malignancy with adjacent metastasis on Computed Tomography (CT) that were further delineated with Magnetic Resonance Imaging (MRI) and [68Ga]-DOTA-(Tyr3)-octreotate (DOTA-TATE) Positron Emission Tomography-Computed Tomography (PET-CT) and surgical pathology as two distinct entities: left epicardial paraganglioma and anterior mediastinal thymoma. A comprehensive discussion of both entities is included.

Author Biographies

Matthew G Dudgeon

Department of Radiology

Mayo Clinic, Jacksonville, FL

Sushilkumar K Sonavane

Department of Radiology

Division of Cardiothoracic Imaging

Mayo Clinic, Jacksonville, FL

Ephraim E Parent

Department of Radiology

Division of Nuclear Medicine

Mayo Clinic, Jacksonville, FL

Andras Khoor

Department of Laboratory Medicine and Pathology

Mayo Clinic, Jacksonville, FL

Mathew Thomas

Department of Cardiovascular/Thoracic Surgery

Mayo Clinic, Jacksonville, FL

Co-existent Epicardial Paraganglioma and Anterior Mediastinal Thymoma by Matthew G Dudgeon et. al.

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Published

2020-10-26

Issue

Vol. 14 No. 10 (2020)

Section

Cardiac Imaging

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