Metronidazole induced encephalopathy: case report and discussion on the differential diagnoses, in particular, Wernicke's encephalopathy

Authors

  • Wenlu Hou
  • Raphael Shih Zhu Yiin
  • Chin Kong Goh

DOI:

https://doi.org/10.3941/jrcr.v13i9.3739

Keywords:

Metronidazole induced encephalopathy, Wernicke's encephalopathy, cerebellar dysfunction, dentate nuclei, magnetic resonance imaging

Abstract

Metronidazole induced encephalopathy is a rare central nervous system toxicity, which may be completely reversible with prompt cessation of metronidazole usage. We present a case of metronidazole induced encephalopathy in a 59-year-old man with a history of Whipple's procedure for pancreatic neuroendocrine tumour. The characteristic magnetic resonance imaging features of metronidazole induced encephalopathy and its main differential diagnosis, Wernicke's encephalopathy, are discussed.

Author Biographies

Wenlu Hou

Department of Radiology, Changi General Hospital, 2 Simei Street 3, Singapore 529889

 

Raphael Shih Zhu Yiin

Department of Radiology, Changi General Hospital, 2 Simei Street 3, Singapore 529889

Chin Kong Goh

Department of Radiology, Changi General Hospital, 2 Simei Street 3, Singapore 529889

Published

2019-09-20

Issue

Section

Neuroradiology