Contrast-enhanced ultrasound findings of post-transplant lymphoproliferative disorder in a transplanted kidney: A case report and literature review

Authors

  • Alyssa Lampe
  • Vinay A Duddalwar
  • Hooman Djaladat
  • Manju Aron
  • Mittul Gulati

DOI:

https://doi.org/10.3941/jrcr.v9i10.2602

Keywords:

Contrast enhanced ultrasound, renal transplant, lymphoma, post-transplant lymphoproliferative disorder

Abstract

Post-transplant lymphoproliferative disorder occurs in approximately one percent of kidney transplant recipients. We evaluated a seventy-seven year-old man with a solid mass in his transplant kidney. On contrast enhanced ultrasound, the mass enhanced but remained persistently hypovascular throughout exam. The enhancement pattern of the mass differed from that typical of clear cell renal cell carcinoma, the main differential diagnosis. Final pathology after partial nephrectomy confirmed post-transplant lymphoproliferative disorder. This is the first report of contrast enhanced ultrasound findings in a renal mass diagnosed as post-transplant lymphoproliferative disorder. Contrast enhanced ultrasound has a promising role in imaging of renal masses, particularly relevant in transplant patients due to the lack of nephrotoxicity.

Author Biographies

Alyssa Lampe

Department of RadiologyKeck School of MedicineUniversity of Southern California

Vinay A Duddalwar

Associate Professor of Radiology
Section Chief, Abdominal Imaging , USCMedical Director, Imaging, Norris Cancer Center
Keck School of Medicine
University of Southern California

Hooman Djaladat

Associate Professor of Clinical UrologyInstitute of UrologyNorris Cancer Center, USCKeck School of Medicine
University of Southern California

Manju Aron

Associate Professor of Clinical PathologyKeck School of MedicineUniversity of Southern California    

Mittul Gulati

Assistant Professor of Clinical RadiologyKeck School of Medicine University of Southern California

Published

2015-10-28

Issue

Section

Genitourinary Radiology