IgG4-Related Disease Presenting as a Solitary Neck Mass

Authors

  • Tyler McKinnon
  • William Thoburn Randazzo
  • Brian David Kim
  • Paul Biddinger
  • Scott Forseen

DOI:

https://doi.org/10.3941/jrcr.v9i2.1993

Keywords:

IgG4 related disease, neck mass, sclerosing disease, autoimmune

Abstract

IgG4-related disease is a newly recognized entity associated with autoimmune conditions involving almost every organ system. It is characterized by elevated serum IgG4 as well as mass like tissue infiltration by IgG4-positive plasma cells. Imaging findings are nonspecific, vary depending on the site of disease, and include mass like enlargement of the salivary or lacrimal glands and enlarged lymph nodes. Radiographic findings often mimic malignancy, necessitating tissue sampling to confirm the diagnosis. Distinguishing IgG4-related disease from malignancy is important as IgG4 responds well to steroids and conservative management.

Author Biographies

Tyler McKinnon

Medical Student, Department of Radiology, Georgia Regents University, 1120 15th Street, Augusta, GA, 30904, USA

William Thoburn Randazzo

Resident, Department of Radiology, Georgia Regents University, 1120 15th Street, Augusta, GA, 30904, USA

Brian David Kim

Resident, Department of Pathology, Georgia Regents University, BF-110, 1120 15th Street, Augusta, GA, 30912, USA

Paul Biddinger

Chief of Anatomic Pathology, Department of Pathology, Georgia Regents University, BF-110, 1120 15th Street, Augusta, GA, 30912, USA

Scott Forseen

Assistant Professor, Section of Neuroradiology, Department of Radiology, Georgia Regents University, 1120 15th Street, Augusta, GA, 30904, USA
Journal of Radiology Case Reports February 2015 issue - Cover page: Pulmonary Imaging Abnormalities in an Adult Case of Congenital Lobar Emphysema by Damien Pike et al.

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Published

2015-02-23

Issue

Vol. 9 No. 2 (2015)

Section

Neuroradiology

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