Erdheim-Chester disease with rare radiological features in a 14-year old girl with pre-B Acute Lymphocytic Leukemia and Diabetes mellitus

Authors

  • Varanasi Venkata Rama Krishna
  • Teo Eu Leong Harvey James
  • Kenneth Tou En Chang
  • Soh Shui Yen

DOI:

https://doi.org/10.3941/jrcr.v8i8.1899

Keywords:

Erdheim-Chester disease, Langerhans cell histiocytosis, osteolytic lesions, Touton type giant cells, Interferon alpha

Abstract

We report a case of a 14 year-old girl with Diabetes Mellitus who was in remission with pre-B cell Acute Lymphoblastic Leukemia and subsequently diagnosed with Erdheim-Chester disease.  Erdheim-Chester disease is a non-Langerhans cell histiocytosis and is very rare in children.  In addition, the radiological features of the lesions are atypical and have not been reported in children.  There is no known association between the three conditions and this is the first reported case in the literature.  A literature review of Erdheim-Chester disease will be performed.

Published

2014-08-25

Issue

Section

Pediatric Radiology