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Click Two-year-old girl diagnosed with Neurocutaneous Melanosis (NCM). Tranfontanellar ultrasonography image shows a mildly increased echogenicity of bilateral amygdalae. Transfontanellar ultrasonography (Siemens SONOLINE Elegra, 2.5PL20/2.6 - Probe/frequency [MHz]).

Click Two-year-old girl diagnosed with Neurocutaneous Melanosis (NCM). Axial non-enhanced CT image (Siemens Emotion Duo, Forchheim, Germany. Slice thickness (ST): 2mm, kVP:130, mAS:200 with total DLP: 687 mGy cm) which was obtained when the patient was one month old, demonstrates mild hyperattenuation in the cerebellum, enlargement of cisterna magna, and dilatation of the lateral ventricles and the third ventricle.

Click Two-year-old girl diagnosed with Neurocutaneous Melanosis (NCM). Precontrast axial T1-weighted (W) MRI (ST:5mm, TR/TE: 488/14.3ms) shows T1 shortening in bilateral amygdalae, pons, cerebellar cortex, and bilateral sixth cranial nerves.

Click Two-year-old girl diagnosed with Neurocutaneous Melanosis (NCM). Precontrast sagittal T1W image (TR/TE: 501/14.3ms, ST:5 mm) demonstrates T1 shortening in the cerebellum, pons, and anterior mesencephalon. Cisterna magna is enlarged. The both lateral ventricles and third ventricle are dilated.

Click Two-year-old girl diagnosed with Neurocutaneous Melanosis (NCM). Axial T2W image (TR/TE:5200/122.4, ST:5 mm) demonstrates that lesions in bilateral amygdalae and cerebellum are slightly hypointense.

Click Two-year-old girl diagnosed with Neurocutaneous Melanosis (NCM). Precontrast axial T1W image (TR/TE: 488/14.3ms, ST:5mm) shows mild hyperintensity of bilateral ventral aspect of thalami.

Click Two-year-old girl diagnosed with Neurocutaneous Melanosis (NCM). Axial diffusion-weighted image (isovolumetric, maximum b value: 700 s/mm2) show no signal alterations in the cerebellum and amygdalae.

Click Two-year-old girl diagnosed with Neurocutaneous Melanosis (NCM). Axial gradient-echo T2* images show no signal alterations in the cerebellum and amygdalae.