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Click 37 year old woman with Neurocandidiasis. Siemens 1.5 Tesla MR. Axial FLAIR stack reveals subtle punctate areas of T2 prolongation in the bilateral basal ganglia, specifically within the globus pallidus. There is no mass effect or midline shift.

Click 37 year old woman with Neurocandidiasis. Siemens 1.5 Tesla MR. Axial T2 weighted sequence.

Click 37 year old woman with Neurocandidiasis. Siemens 1.5 Tesla MR with diffusion weighting. Several punctate foci of increased signal intensity within the bilateral basal ganglia suggestive of restricted diffusion.

Click 37 year old woman with Neurocandidiasis. Siemens 1.5 Tesla MR axial ADC map confirms multiple punctate foci of restricted diffusion (DWI bright, ADC dark) within the bilateral basal ganglia.

Click 37 year old woman with Neurocandidiasis. Siemens 1.5 Tesla MR axial gradient echo sequence shows no significant abnormalities except for generalized widening of ventricles and subarachnoid spaces.

Click 37 year old woman with Neurocandidiasis. Siemens 1.5 Tesla MR pre-contrast T1 weighted MRI demonstrates no significant parenchymal abnormalities except for generalized widening of ventricles and subarachnoid spaces. An extra-axial T1 hyperintense collection is present in the right frontal region consistent with a small subdural collection.

Click 37 year old woman with Neurocandidiasis. Siemens 1.5 Tesla MR sagittal T1 weighted MRI demonstrates no significant midline abnormalities. Generalized prominence of ventricles and sulci is noted.

Click 37 year old woman with Neurocandidiasis. Siemens 1.5 Tesla MR after the administration of 15 mL intravenous Magnevist. Axial post-contrast T1 weighted MRI demonstrate no definite areas of abnormal enhancement. There is mild prominence of the lateral ventricles and sulci.

Click 37 year old woman with Neurocandidiasis. Siemens 1.5 Tesla MR after the administration of 15 mL intravenous Magnevist. Coronal post-contrast T1 weighted MRI demonstrates no definite areas of abnormal contrast enhancement.

Click 37 year old woman with Neurocandidiasis. One month follow-up examination performed for worsening symptoms in the same patient. Siemens 1.5 Tesla MR axial FLAIR sequence demonstrates interval increased bilateral basal ganglia T2 prolongation, which is now clearly more confluent.

Click 37 year old woman with Neurocandidiasis. One month follow-up examination performed for worsening symptoms in the same patient. Siemens 1.5 Tesla MR axial T2 weighted MR sequence demonstrates T2 hyperintensity within the bilateral basal ganglia.

Click 37 year old woman with Neurocandidiasis. One month follow-up examination performed for worsening symptoms in the same patient. Siemens 1.5 Tesla MR diffusion weighted images demonstrate marked progression in previously noted multiple small foci of restricted diffusion within the basal ganglia, which are now more confluent. There are interval additional foci of diffusion restriction: a moderate sized area involving the right sensory and motor strip and right insular cortex with additional smaller foci scattered throughout the cerebral hemispheres. Two punctate foci are additionally seen within the superior cerebellum bilaterally.

Click 37 year old woman with Neurocandidiasis. One month follow-up examination performed for worsening symptoms in the same patient. Siemens 1.5 Tesla MR axial ADC map corresponds to the axial diffusion weighted image (axial DWI) and confirms marked progression of restricted diffusion within the basal ganglia. There are also new areas of restricted diffusion within the right sensory and motor strips and bilateral cerebellum.

Click 37 year old woman with Neurocandidiasis. One month follow-up examination performed for worsening symptoms in the same patient. Siemens 1.5 Tesla MR axial gradient echo sequence demonstrates multiple punctate hyperintense areas within the bilateral basal ganglia.

Click 37 year old woman with Neurocandidiasis. One month follow-up examination performed for worsening symptoms in the same patient. Siemens 1.5 Tesla MR pre-contrast T1 weighted MRI demonstrates high T1 signal associated with restricted diffusion in the basal ganglia suggestive of small foci of hemorrhage. There is no significant mass effect. Ventricles, sulci, and cisterns are within normal limits.

Click 37 year old woman with Neurocandidiasis. One month follow-up examination performed for worsening symptoms in the same patient. Siemens 1.5 Tesla MR sagittal T1 weighted MRI demonstrates T1 hyperintensity in the basal ganglia. There is generalized prominence of ventricles and sulci.

Click 37 year old woman with Neurocandidiasis. One month follow-up examination performed for worsening symptoms in the same patient. Siemens 1.5 Tesla MR after the administration of 20 mL intravenous Magnevist. Post-contrast T1 weighted MRI demonstrates striking enhancement of lesions within the basal ganglia.

Click 37 year old woman with Neurocandidiasis. One month follow-up examination performed for worsening symptoms in the same patient. Siemens 1.5 Tesla MR after administration of 20 mL intravenous Magnevist. Coronal post-contrast T1 weighted MRI demonstrates striking enhancement within the bilateral basal ganglia. There is also enhancement noted in the right superior parietal lobe.