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Click 57-year-old man with radiation necrosis of the pons. Contrast-enhanced MP-RAGE (1D-F) MRI demonstrates two well-circumscribed peripherally contrast-enhancing lesions (arrow) in the pons measuring 14 and 15 mm respectively. The lesions are hypointense on pre-contrast T1 (1A) and are associated with diffuse FLAIR (1B) edema that extends into the medulla and right inferior cerebellar peduncle. There is no obvious mass effect and no extension of the lesion beyond the boundaries of the pons, notably into the cerebellopontine angle or the prepontine cistern. DWI (1C) showed no diffusion abnormality. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.3ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 10mL of gadopentate dimeglumine (Magnevist))

Click 57-year-old man with radiation necrosis of the pons. Contrast-enhanced MP-RAGE (1D-F) MRI demonstrates two well-circumscribed peripherally contrast-enhancing lesions (arrow) in the pons measuring 14 and 15 mm respectively. The lesions are hypointense on pre-contrast T1 (1A) and are associated with diffuse FLAIR (1B) edema that extends into the medulla and right inferior cerebellar peduncle. There is no obvious mass effect and no extension of the lesion beyond the boundaries of the pons, notably into the cerebellopontine angle or the prepontine cistern. DWI (1C) showed no diffusion abnormality. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.3ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 10mL of gadopentate dimeglumine (Magnevist))

Click 57-year-old man with radiation necrosis of the pons. Contrast-enhanced MP-RAGE (1D-F) MRI demonstrates two well-circumscribed peripherally contrast-enhancing lesions (arrow) in the pons measuring 14 and 15 mm respectively. The lesions are hypointense on pre-contrast T1 (1A) and are associated with diffuse FLAIR (1B) edema that extends into the medulla and right inferior cerebellar peduncle. There is no obvious mass effect and no extension of the lesion beyond the boundaries of the pons, notably into the cerebellopontine angle or the prepontine cistern. DWI (1C) showed no diffusion abnormality. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.3ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 10mL of gadopentate dimeglumine (Magnevist))

Click 57-year-old man with radiation necrosis of the pons. Contrast-enhanced MP-RAGE (1D-F) MRI demonstrates two well-circumscribed peripherally contrast-enhancing lesions (arrow) in the pons measuring 14 and 15 mm respectively. The lesions are hypointense on pre-contrast T1 (1A) and are associated with diffuse FLAIR (1B) edema that extends into the medulla and right inferior cerebellar peduncle. There is no obvious mass effect and no extension of the lesion beyond the boundaries of the pons, notably into the cerebellopontine angle or the prepontine cistern. DWI (1C) showed no diffusion abnormality. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.3ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 10mL of gadopentate dimeglumine (Magnevist))

Click 57-year-old man with radiation necrosis of the pons. Contrast-enhanced MP-RAGE (1D-F) MRI demonstrates two well-circumscribed peripherally contrast-enhancing lesions (arrow) in the pons measuring 14 and 15 mm respectively. The lesions are hypointense on pre-contrast T1 (1A) and are associated with diffuse FLAIR (1B) edema that extends into the medulla and right inferior cerebellar peduncle. There is no obvious mass effect and no extension of the lesion beyond the boundaries of the pons, notably into the cerebellopontine angle or the prepontine cistern. DWI (1C) showed no diffusion abnormality. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.3ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 10mL of gadopentate dimeglumine (Magnevist))

Click 57-year-old man with radiation necrosis of the pons. Contrast-enhanced MP-RAGE (1D-F) MRI demonstrates two well-circumscribed peripherally contrast-enhancing lesions (arrow) in the pons measuring 14 and 15 mm respectively. The lesions are hypointense on pre-contrast T1 (1A) and are associated with diffuse FLAIR (1B) edema that extends into the medulla and right inferior cerebellar peduncle. There is no obvious mass effect and no extension of the lesion beyond the boundaries of the pons, notably into the cerebellopontine angle or the prepontine cistern. DWI (1C) showed no diffusion abnormality. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.3ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 10mL of gadopentate dimeglumine (Magnevist))

Click 57-year-old man with radiation necrosis of the pons. Compared to the prior study (figure 1), there is interval size reduction and normalization (arrow) in the T1 (3A) hypointensity, FLAIR (3B) pontine signal abnormality and the associated contrast enhancement on MP-RAGE (3D-F). DWI (3C) continues to show no diffusion abnormality. There is no obvious mass effect of the pontine and cerebellar peduncle lesions and no extension beyond the boundary of the brainstem. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.4ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3ms, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 13mL of gadopentate dimeglumine (Magnevist))

Click 57-year-old man with radiation necrosis of the pons. Compared to the prior study (figure 1), there is interval size reduction and normalization (arrow) in the T1 (3A) hypointensity, FLAIR (3B) pontine signal abnormality and the associated contrast enhancement on MP-RAGE (3D-F). DWI (3C) continues to show no diffusion abnormality. There is no obvious mass effect of the pontine and cerebellar peduncle lesions and no extension beyond the boundary of the brainstem. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.4ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3ms, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 13mL of gadopentate dimeglumine (Magnevist))

Click 57-year-old man with radiation necrosis of the pons. Compared to the prior study (figure 1), there is interval size reduction and normalization (arrow) in the T1 (3A) hypointensity, FLAIR (3B) pontine signal abnormality and the associated contrast enhancement on MP-RAGE (3D-F). DWI (3C) continues to show no diffusion abnormality. There is no obvious mass effect of the pontine and cerebellar peduncle lesions and no extension beyond the boundary of the brainstem. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.4ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3ms, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 13mL of gadopentate dimeglumine (Magnevist))

Click 57-year-old man with radiation necrosis of the pons. Compared to the prior study (figure 1), there is interval size reduction and normalization (arrow) in the T1 (3A) hypointensity, FLAIR (3B) pontine signal abnormality and the associated contrast enhancement on MP-RAGE (3D-F). DWI (3C) continues to show no diffusion abnormality. There is no obvious mass effect of the pontine and cerebellar peduncle lesions and no extension beyond the boundary of the brainstem. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.4ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3ms, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 13mL of gadopentate dimeglumine (Magnevist))

Click 57-year-old man with radiation necrosis of the pons. Compared to the prior study (figure 1), there is interval size reduction and normalization (arrow) in the T1 (3A) hypointensity, FLAIR (3B) pontine signal abnormality and the associated contrast enhancement on MP-RAGE (3D-F). DWI (3C) continues to show no diffusion abnormality. There is no obvious mass effect of the pontine and cerebellar peduncle lesions and no extension beyond the boundary of the brainstem. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.4ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3ms, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 13mL of gadopentate dimeglumine (Magnevist))

Click 57-year-old man with radiation necrosis of the pons. Compared to the prior study (figure 1), there is interval size reduction and normalization (arrow) in the T1 (3A) hypointensity, FLAIR (3B) pontine signal abnormality and the associated contrast enhancement on MP-RAGE (3D-F). DWI (3C) continues to show no diffusion abnormality. There is no obvious mass effect of the pontine and cerebellar peduncle lesions and no extension beyond the boundary of the brainstem. (A: 1.5 Tesla, TR 400ms, TE 16ms, slice thickness 5.0mm, B: TR 8602ms, TE 129.4ms, slice thickness 5.0mm, C: TR 10000ms, TE 98.3ms, slice thickness 5.0mm, D: TR 8.4ms, TE 2.6ms, slice thickness 1.6mm. E-F: TR 8.4ms, TE 2.6ms, slice thickness 1.5mm; A-C without contrast, D-F with 13mL of gadopentate dimeglumine (Magnevist))