The Teaching Point

The association of pelvic masses with heterogenous T2-signal and pelvic intraperitoneal fluid do not necessarily imply the presence of a malignant neoplasia but it is often related to degenerative aspects in large fibromas and fibrothecomas. In the differential diagnosis clinical and radiological features must be taken into account globally to identify possible Nevoid Basal Cell Carcinoma Syndrome.






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From the manuscript

Imaging features of uterine and ovarian fibromatosis in Nevoid Basal Cell Carcinoma Syndrome

Free full text article: Imaging features of uterine and ovarian fibromatosis in Nevoid Basal Cell Carcinoma Syndrome

Abstract
Gorlin-Goltz Syndrome also known as Nevoid Basal Cell Carcinoma Syndrome is an autosomal dominant multisystem disorder. It is characterized by basal cell carcinomas, odontogenic keratocysts, skeletal abnormalities and in a minority of female patients bilateral calcified ovarian fibromas. It is challenging to radiologically assess ovarian fibromas as they have similar imaging patterns to some malignant ovarian lesions. However, it is vitally important to differentiate between benign and malignant lesions to determine patients` suitability for fertility-sparing surgery. This report describes a case of a 25 year-old patient with Gorlin-Goltz Syndrome and bilateral ovarian fibromas.






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