The Teaching Point

Although splenules are usually incidental findings of little clinical importance, these lesions may require further evaluation, particularly in patients with a history of malignancy. Fused SPECT/CT imaging with Tc-99m labeled denatured red blood cells facilitates the definitive diagnosis of a splenule and may also help in identifying splenules that have relocated within the abdominal cavity.






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From the manuscript

SPECT/CT imaging of a retroperitoneal nodule in a patient with history of infiltrating renal urothelial carcinoma

Free full text article: SPECT/CT imaging of a retroperitoneal nodule in a patient with history of infiltrating renal urothelial carcinoma

Abstract
A 62 year old woman status post radical nephroureterectomy for high grade urothelial carcinoma was found on CT to have a 1 cm retroperitoneal nodule in the nephrectomy bed. The nodule`s differential diagnosis included recurrent urothelial carcinoma versus relocation of the patient`s splenule seen on earlier CT imaging. We report using SPECT/CT with Tc-99m labeled denatured red blood cells to definitively diagnose the nodule as a relocated splenule.






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