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In a 20 year old with acute severe chest pain and dyspnea, there was 3He MRI and CT evidence of congenital lobar emphysema in the LUL that was not evident using clinical spirometry or diffusing capacity breathing tests. In young adults with recent and sudden onset of chest pain and dyspnea, the presence and diagnosis of congenital lobar emphysema with or without bronchial atresia can be made using anatomical high resolution CT and functional/ventilation imaging using CT or MRI.






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Pulmonary Imaging Abnormalities in an Adult Case of Congenital Lobar Emphysema

Free full text article: Pulmonary Imaging Abnormalities in an Adult Case of Congenital Lobar Emphysema

Abstract
Congenital lobar emphysema is mainly diagnosed in infants, although rare cases are reported in adults. A 20-yr-old female with acute dyspnea, chest pain and left upper lobe (LUL) chest x-ray hyperlucency underwent 3He magnetic resonance imaging (MRI) for ventilation and apparent diffusion coefficient (ADC) measurements, as well as CT for emphysema and airway wall measurements. Forced expiratory volume in 1s, residual volume, and airways-resistance were abnormal, but there was normal carbon-monoxide-diffusing-capacity. The LUL relative area of the density histogram <-950 HU and airway morphology were highly abnormal compared with the other lobes and coincident with highly abnormal MRI-derived acinar duct dimensions. CT also identified bronchial atresia and congenital lobar emphysema as the source of symptoms in this case where there was also functional imaging evidence of collateral ventilation from the fissure (and not the abnormally terminated airway) into the emphysematous LUL.






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1. Congenital Lobar Emphysema

2. Bronchial Atresia

3. Hyperpolarized 3He

4. Magnetic Resonance Imaging

5. Computed Tomography

6. Emphysema

7. Airways Disease


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