The Teaching Point

In order to find a cause of ACTH dependent Cushing's syndrome due to Neuroendocrine tumors, multi-imaging modalities are needed. Massive bilateral adrenal gland hyperplasia indirectly implies increased ACTH production and brain MRI helps to rule out pituitary tumors, which is a common cause for ACTH dependent Cushing's syndrome. Combined 111In-pentetreotide SPECT/CT locates the site of the tumor by detecting somatostatin receptors which are often plentiful in Neuroendocrine tumor.






Bookmark and Share

From the manuscript

CT and 111In-pentetreotide SPECT of hilar ACTH-producing neuroendocrine tumor associated with Cushing`s syndrome and massive bilateral adrenal gland hyperplasia

Free full text article: CT and 111In-pentetreotide SPECT of hilar ACTH-producing neuroendocrine tumor associated with Cushing`s syndrome and massive bilateral adrenal gland hyperplasia

Abstract
We present the clinical, laboratory, computed tomography (CT), single photon emission computed tomography (SPECT), and histopathological findings of a patient with adrenocorticotropic hormone (ACTH) dependent Cushing`s syndrome with massive bilateral adrenal gland hyperplasia due to a hilar ACTH-producing well-differentiated neuroendocrine carcinoma.






References



1. Newell-Price J, Bertagna X, Grossman AB, Nieman LK. Cushing`s syndrome. Lancet 2006 May 13;367(9522):1605-17.
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


2. Makras P, Toloumis G, Papadogias D, Kaltsas GA, Besser M. The diagnosis and differential diagnosis of endogenous Cushing`s syndrome. Hormones (Athens) 2006 Oct-Dec;5(4):231-50.
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


3. Yao JC, Hassan M, Phan A, Dagohoy C, Leary C, Mares JE. One hundred years after "carcinoid": epidemiology of and prognostic factors for neuroendocrine tumors in 35,825 cases in the United States. J Clin Oncol 2008 Jun 20;26(18):3063-72.
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


4. Arnold R. Endocrine tumors of the gastrointestinal tract; Introduction: definition, historical aspects, classification, staging, prognosis and therapeutic options. Best Pract Res Clin Gastroenterol 2005 Aug;19(4):491-505.
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


5. Ancion G, Hennen G. Cushing syndromes due to aberrant expression of functional receptors other than ACTH; A new organic hypercorticism syndrome entity. Rev Med Liege 2000 Oct;55(10):929-34.
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


6. Doppman JL, Chrousos GP, Papanicolaou DA, Stratakis CA, Alexander HR, Nieman LK. Adrenocorticotropin-independent macronodular adrenal hyperplasia: an uncommon cause of primary adrenal hypercortisolism. Radiology 2000 Sep;216(3):797-802.
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


7. De Herder WW, Kwekkeboom DJ, ValkemaR, Feelders RA, van Aken MO, Lamberts SW, van der Lely AJ, Krenning EP. Neuroendocrine tumors and somatostatin: imaging techniques. J Endocrinol Invest 2005;28(11 Suppl International):132-6.
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


8. Tsagarakis S, Christoforaki M, Giannopoulou H, Rondogianni F, Housianakou I, Malagari C. A reappraisal of the utility of somatostatin receptor scintigraphy in patients with ectopic adrenocorticotropin Cushing`s syndrome. J Clin Endocrinol Metab 2003 Oct;88(10):4754-8.
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine




Search for articles with similar topics:

Keyword search:

1. Bilateral adrenal gland hyperplasia

2. 111In-pentetreotide (Octreoscan)

3. Cushing`s syndrome


This article belongs to the GU section.


Search for more in the Internet

Peer-reviewed Radiology Search




Discuss it!

Bookmark and Share




© Journal of Radiology Case Reports - The Interactive Radiology Journal
Affiliated journal of Radiolopolis - The International Radiology Community


The Journal of Radiology Case Reports