The Teaching Point

Lupus mastitis is important to include as a differential consideration in Lupus patients with a breast mass, because treatment and prognosis are markedly different than with malignancy. In cases where clinical history is ambiguous and tissue diagnosis is necessary, core needle biopsy is preferred over surgical excision because it is less likely to exacerbate lupus mastitis. In the setting of suspected lupus mastitis, serial MRI exams may be useful in evaluating response to therapy as there appears to be a correlation between the decreasing thickness of peripheral enhancement and clinical resolution of symptoms.






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From the manuscript

Serial MR Findings and Comprehensive Review of Bilateral Lupus Mastitis with an Additional Case Report

Free full text article: Serial MR Findings and Comprehensive Review of Bilateral Lupus Mastitis with an Additional Case Report

Abstract
Lupus Mastitis (LM) is a rare presentation of lupus panniculitis involving the breast. Because it often presents as a tender palpable mass, a workup for malignancy usually ensues. It is well documented that surgery may worsen the condition; therefore, it is important to consider LM in the differential of a palpable breast mass in patients with systemic lupus erythematosus (SLE). Currently, management of LM remains primarily medical. We discuss the multi-disciplinary work-up of LM, and further describe its appearance on serial Magnetic Resonance (MR) exams.






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