The Teaching Point

If focal pain is present or develops in the area of a known chondroid lesion, it is highly suspicious and biopsy should strongly be considered regardless of its imaging features. Endosteal scalloping greater than 2/3 of the cortical width is highly suspicious and biopsy should strongly be considered even if the patient is clinically asymptomatic. It is reasonable to follow indeterminate lesions with serial, close-interval, cross-sectional imaging at 4-6 months for the first 2 years, then annually for a total of 5 years. This is especially important in a pediatric patient who may not be able to accurately localize their pain.






Bookmark and Share

From the manuscript

Chondrosarcoma in Childhood: The Radiologic and Clinical Conundrum

Free full text article: Chondrosarcoma in Childhood:  The Radiologic and Clinical Conundrum

Abstract
Less than 10% of chondrosarcomas occur in children. In addition, as little as 0.5% of low-grade chondrosarcomas arise secondarily from benign chondroid lesions. The presence of focal pain is often used to crudely distinguish a chondrosarcoma (which is usually managed with wide surgical excision), from a benign chondroid lesion (which can be followed by clinical exams and imaging surveillance). Given the difficulty of localizing pain in the pediatric population, initial radiology findings and short-interval follow-up, both imaging and clinical, are critical to accurately differentiate a chondrosarcoma from a benign chondroid lesion. To our knowledge, no case in the literature discusses a chondrosarcoma possibly arising secondarily from an enchondroma in a pediatric patient. We present a clinicopathologic and radiology review of conventional chondrosarcomas. We also attempt to further the understanding of how to manage a chondroid lesion in the pediatric patient with only vague or bilateral complaints of pain.






References



1. Murphey MD. From the Archives of AFIP - Imaging of Primary Chondrosarcoma: Radiologic-Pathologic Correlation. RadioGraphics 2003; 23:1245-1278 PubMed ID: 12975513
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


2. Hameed M, Dorfman H. Pimary Malignant Bone Tumors - Recent Developments. Semin Diagn Pathol 2011 Feb;28(1):86-101
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


3. Kaste SC. Imaging Pediatric Bone Sarcomas. Radiol Clin North Am 2011 Jul;49(4):749-65, vi-vii
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


4. Soldatos T. Imaging Features of Chondrosarcoma. J Comput Assist Tomogr 2011 Jul-Aug;35(4):504-11
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


5. Wootton-Gorges SL. MR imaging of primary bone tumors and tumor-like conditions in children. Magn Reson Imaging Clin N Am 2009 Aug;17(3):469-87, vi
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


6. Dähnert, Wolgang. Dähnert, Radiology Review Manual, 7th ed. Lippincott Williams & Wilkins, 2011.
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


7. Küpeli S. Sacral mesenchymal chondrosarcoma in childhood: a case report and review of the literature. Pediatr Hematol Oncol 2010 Oct;27(7):564-73
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


8. Zibis AH. Case Report: Mesenchymal Chondrosarcoma of the Lumbar Spine in a Child. Clin Orthop Relat Res 2010 Aug;468(8):2288-94
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


9. Kim S. Pediatric Rib Lesions: A 13 year experience. J Pediatr Surg 2008 Oct;43(10):1781-5
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


10. Ilaslan H. Clinical Presentation and Imaging of Bone and Soft Tissue Sarcomas. Cleve Clin J Med 2010 Mar;77 Suppl 1:S2-7
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


11. Feldman F, Van HR, Saxena C. 18FDG-PET applications for cartilage neoplasms. Skeletal Radiol 2005;34(7):367-74 PubMed ID: 15937711
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


12. Papachristou DJ, Gkretsi V, Rao UN. Expression of integrin-linked kinase and its binding partners in chondrosarcoma: association with prognostic significance. Eur J Cancer 2008;44(16):2518-25 PubMed ID: 18722108
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


13. Sardi I. Intracranial mesenchymal chondrosarcoma: report of two pediatric cases. Pediatr Blood Cancer 2011 Apr;56(4):685-6
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine




Search for articles with similar topics:

Keyword search:

1. pediatric chondrosarcoma

2. chondrosarcoma

3. bone tumor

4. pediatric


This article belongs to the Pediatric section.


Search for more in the Internet

Peer-reviewed Radiology Search




Discuss it!

Bookmark and Share




© Journal of Radiology Case Reports - The Interactive Radiology Journal
Affiliated journal of Radiolopolis - The International Radiology Community


The Journal of Radiology Case Reports