Question:

What is the most common site of fetus-in-fetu?
1. Central nervous system.
2. Retroperitoneum.
3. Gastrointestinal system.
4. Extremities.
5. Gonads.





Answer:

The correct answer for the question "What is the most common site of fetus-in-fetu?" is:

2. Retroperitoneum.



Explanation
FIF results when unequal division of the totipotent inner cell mass of the developing blastocyst allows one twin being trapped within a maturing sibling embryo. Pathogenesis is unknown; however it is proposed that during process of ventral folding of trilaminar embryonic disc, one of the fetuses is enclosed in its host because of persistent anastomoses of vitelline circulation. As superior mesenteric artery develops from vitelline circulation, thereby explaining the retroperitoneal location of FIF. Uncommon sites are oral cavity, sacrococcygeal region, scrotum, cranium, GIT, vessels, lungs, adrenal glands, spleen, lymph nodes and genitourinary system of host twin.



From the manuscript:
Diagnostic dilemma in a neglected case of fetus-in-fetu solved with Magnetic Resonance Imaging and MDCT - a case report and review of literature
Radiology Case. 2011 Oct; 5(10):29-37


This article belongs to the Pediatric section.




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From the manuscript

Diagnostic dilemma in a neglected case of fetus-in-fetu solved with Magnetic Resonance Imaging and MDCT - a case report and review of literature

Free full text article: Diagnostic dilemma in a neglected case of fetus-in-fetu solved with Magnetic Resonance Imaging and MDCT - a case report and review of literature

Abstract
Fetus-in-fetu (FIF) is a rare anomaly in which a vertebrate fetus is enclosed within the body of its twin in diamniotic monochorionic pregnancy. To the best of our knowledge, fewer than 100 cases have been reported in literature. Although a wide variety of presentations have been described in clinical reports, the characteristic features on MRI which distinguish FIF from teratoma have not been well delineated. Here we present a case of fetus-in-fetu in which characteristic MDCT and MR findings were used to diagnose FIF preoperatively and successfully differentiate it from teratoma. Although both CT and MRI can be used for definitive preoperative diagnosis of FIF, MRI is an ideal imaging modality due to inherent high tissue contrast and spatial resolution. Furthermore, MRI obviates the need for iodine contrast and eliminates the risk of ionizing radiation. We emphasize that MRI is an ideal valuable diagnostic tool for definite preoperative diagnosis of FIF and surgical planning.






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1. fetus-in-fetu

2. teratoma

3. axial skeleton

4. diamniotic monochorionic twins

5. parasitic twin

6. multidetector computed tomography, magnetic resonance imaging


This article belongs to the Pediatric section.


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