Question:

What disease process is the most common cause of sinistral portal hypertension?
1. Liver Cirrhosis
2. Peptic Ulcer Disease
3. Thrombophlebitis
4. Chronic Pancreatis
5. Superior Mesenteric artery thrombosis





Answer:

The correct answer for the question "What disease process is the most common cause of sinistral portal hypertension?" is:

4. Chronic Pancreatis



Explanation
The most common process leading sinistral portal hypertension is pancreatitis. While thrombophlebitis is a less common cause of sinistral portal hypertension, liver cirrhosis, peptic ulcer disease, and superior mesenteric artery thrombosis are not causes of sinistral portal hypertension. [There are several causes of sinistral portal hypertension presented in the literature with the majority of such cases due to a pathology in the pancreas. While chronic pancreatitis is the most common cause, pancreatic pseudocysts, and various pancreatic neoplasms have all been reported as possible causes]



From the manuscript:
Sinistral Portal Hypertension: Presentation, Radiological Findings, and Treatment Options - A Case Report
Radiology Case. 2010 Oct; 4(10):14-20


This article belongs to the Interventional section.




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From the manuscript

Sinistral Portal Hypertension: Presentation, Radiological Findings, and Treatment Options - A Case Report

Free full text article: Sinistral Portal Hypertension: Presentation, Radiological Findings, and Treatment Options - A Case Report

Abstract
Sinistral portal hypertension occurs when a pathological process causes occlusion of the splenic vein. The resultant elevated splenic bed venous pressure causes formation of gastric varices which can lead to hematemesis as a common presentation for this disease process. We present a case of sinistral portal hypertension in a patient with acute hematemesis as the primary presentation. Despite the challenging diagnosis process, the patient underwent splenectomy and was managed appropriately according to previously published literature.






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