Question:

Which of the following is FALSE?
1. FDG PET is likely more accurate than CT for internal mammary nodal metastases.
2. FDG uptake is synovitis is well-described in the literature.
3. FDG uptake in common in inflammatory processes.
4. Radiographic changes may be minimal if the sternoclavicular joint is affected by rheumatoid arthritis
5. FDG PET cannot be used to evaluate the degree of synovitis in a joint





Answer:

The correct answer for the question "Which of the following is FALSE?" is:

5. FDG PET cannot be used to evaluate the degree of synovitis in a joint



Explanation
1.    (FDG PET may be more accurate than CT for the diagnosis of internal mammary and mediastinal nodes in patients with breast cancer).

2.    (FDG uptake in synovitis, particularly related to rheumatoid arthritis, has been well-described and the degree of FDG uptake has been used to monitor disease activity).

3.    (As activated white cells have increased glycolysis, FDG uptake is noted a wide range of inflammatory processes.)

4.     (The sternoclavicular joint can be involved in up to one-third of patients with rheumatoid arthritis, although radiographic changes may be minimal).

5.    (FDG uptake in synovitis, particularly related to rheumatoid arthritis, has been well-described and the degree of FDG uptake has been used to monitor disease activity).



From the manuscript:
FDG uptake in sternoclavicular joint synovitis: Mimic of internal mammary adenopathy.
Radiology Case. 2010 Mar; 4(3):31-34


This article belongs to the Nucs section.




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From the manuscript

FDG uptake in sternoclavicular joint synovitis: Mimic of internal mammary adenopathy.

Free full text article: FDG uptake in sternoclavicular joint synovitis: Mimic of internal mammary adenopathy.

Abstract
False-positive FDG uptake has been noted in a wide range of benign processes. In this report, we describe a case of FDG uptake in unilateral sternoclavicular synovitis which mimicked an internal mammary node in appearance. Knowledge of this potential false-positive is particularly important in breast cancer patients with a propensity of internal mammary nodal metastases.






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