Question:

Which of the following statements is true?
1. Leiomyosarcomas are slow growing tumors.
2. Leiomyomas can metastasize
3. Leiomyomas often present with cachexia and shortness of breath.
4. Leiomyomas often transform into leiomyosarcomas.
5. Leiomyosarcomas most commonly metastsize to the ovary.





Answer:

The correct answer for the question "Which of the following statements is true?" is:

2. Leiomyomas can metastasize



Explanation

Benign metastasizing leiomyomas are a variant of leiomyomas. (A rare variant of this presentation is benign metastasizing leiomyomata. These are histologically benign cells, as evidenced by lack of invasion, and low level of mitosis; however, they have been transported to new locations.)



From the manuscript:
A Leiomyoma in a Cachectic Woman Presenting as a Giant Abdominal Mass
Radiology Case. 2009 Oct; 3(10):23-29


This article belongs to the OB/GYN section.




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From the manuscript

A Leiomyoma in a Cachectic Woman Presenting as a Giant Abdominal Mass

Free full text article: A Leiomyoma in a Cachectic Woman Presenting as a Giant Abdominal Mass

Abstract
Fibroids are the most common gynecologic tumors. Our case discusses the outcome of a 47-year-old woman who presented to our clinic with cachexia, and a giant abdominal mass. An initial diagnostic imaging workup consisted of X-Ray, CT, and ultrasound and indicated a possible diagnosis of leiomyosarcoma. However, after surgical evaluation, she was diagnosed pathologically with an atypical presentation of a uterine leiomyoma. Our case reviews the epidemiology and presentation of both pathologies, along with the imaging workup, and the operative correlation in our patient.






References



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2. Stewart E. Epidemiology, clinical manifestations, diagnosis, and natural history of uterine leiomyomas [serial online] UpToDate, Basow, DS (Ed), UpToDate, Waltham, MA, 2009.
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5. Walker C, Stewart E. Uterine Fibroids: The Elephant in the Room. 2005 Jun 10;308(5728):1589-92
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6. Dumousset E, Chabrot P, Rabischong B. Preoperative Uterine Artery Embolization (PUAE) Before Uterine Fibroid Myomectomy. Cardiovasc Intervent Radiol 2008
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10. Ellenson L, Pirog E. Chapter 22. The Female Genital Tract Kumar V, Abbas A, Fausto N, Aster J
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1. Leiomyoma

2. Fibroids

3. Pelvic Mass

4. cachexia

5. leiomyosarcoma


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