Question:

In regards to solitary fibrous tumor of pleura, please answer with either true or false for each statement.
1. Recent advances demonstrate SFTP to have a mesothelial origin.
2. Recent advances demonstrate SFTP to have a mesenchymal origin.
3. SFTP is strongly correlated with smoking.
4. SFTP has no known correlation with asbestos exposure.
5. Development of SFTP has been reported following radiation therapy to the chest wall.





Answer:

The correct answers for the question "In regards to solitary fibrous tumor of pleura, please answer with either true or false for each statement." are:

2. Recent advances demonstrate SFTP to have a mesenchymal origin.

4. SFTP has no known correlation with asbestos exposure.

5. Development of SFTP has been reported following radiation therapy to the chest wall.



Explanation

a. Recent advances demonstrate SFTP to have a mesothelial origin. (Solitary fibrous tumor of pleura (SFTP) is a rare neoplasm for which recent advances in electron microscopy and immunohistochemistry demonstrate a mesenchymal rather than mesothelial origin.)

b. Recent advances demonstrate SFTP to have a mesenchymal origin. (Solitary fibrous tumor of pleura (SFTP) is a rare neoplasm for which recent advances in electron microscopy and immunohistochemistry demonstrate a mesenchymal rather than mesothelial origin.)

c. SFTP is strongly correlated with smoking. (No link has been established between smoking or environmental exposure (including asbestos), although some SFTP have developed following radiation therapy to the chest wall [4].)

d. SFTP has no known correlation with asbestos exposure. (No link has been established between smoking or environmental exposure (including asbestos), although some SFTP have developed following radiation therapy to the chest wall [4].)

e. Development of SFTP has been reported following radiation therapy to the chest wall. (No link has been established between smoking or environmental exposure (including asbestos), although some SFTP have developed following radiation therapy to the chest wall [4].)



From the manuscript:
Solitary fibrous tumor of pleura: a case report and review of clinical, radiographic and histologic findings
Radiology Case. 2009 May; 3(5):16-20


This article belongs to the Chest section.




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From the manuscript

Solitary fibrous tumor of pleura: a case report and review of clinical, radiographic and histologic findings

Free full text article: Solitary fibrous tumor of pleura: a case report and review of clinical, radiographic and histologic findings

Abstract
We present a case of solitary fibrous tumor of pleura (SFTP) in a 63-year-old male. Clinical manifestations of this entity, including paraneoplastic syndromes, are discussed, albeit absent in our presented case. Furthermore radiographic findings and pathologic correlations are provided. SFTP remains a rare neoplasm for which radiographic features are suggestive yet nonspecific, and immunohistochemistry remains as the diagnostic method of choice.






References



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