Question:

Concerning solitary fibrous tumors, which of the following is true (all that apply)?
1. They are most common in children.
2. They occur more commonly in men.
3. They may cause hypoglycemia.
4. They do not have malignant potential.
5. Their most common location is in the deep tissues of the head and neck.





Answer:

The correct answer for the question "Concerning solitary fibrous tumors, which of the following is true (all that apply)?" is:

3. They may cause hypoglycemia.



Explanation
1.    Solitary fibrous tumors are rare in children. [SFTs tend to occur in adults aged 20-70 and equally in males and females. They are very rare in children.]

2.    Solitary fibrous tumors do not demonstrate a gender predilection.

3.    One paraneoplastic syndrome that can be present with solitary fibrous tumors is hypoglycemia. [Two paraneoplastic syndromes are associated with SFTs: hypoglycemia due to production of an insulin-like growth factor (Doege-Potter syndrome) or hypertrophic osteoarthropathy, neither of which was present in our patient.]

4.    Solitary fibrous tumors can be malignant. [The percentage of SFTs that are found to be malignant varies in the literature, with most studies reporting ranges from 5 to 26% of cases.]

5.    Most solitary fibrous tumors occur in subcutaneous tissue. [SFTs can occur in any site, but most commonly occur in subcutaneous tissue (40%).]



From the manuscript:
Solitary Fibrous Tumor of the Infratemporal Fossa
Radiology Case. 2014 Dec; 8(12):1-8


This article belongs to the Neuro section.




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From the manuscript

Solitary Fibrous Tumor of the Infratemporal Fossa

Free full text article: Solitary Fibrous Tumor of the Infratemporal Fossa

Abstract
Solitary fibrous tumors represent fewer than 2% of all soft tissue tumors, and only about 12-15% of them occur in the head and neck. We report a case of a 38-year-old male who presented with a six-month history of increasing right cheek swelling. Computed tomography of the paranasal sinuses with contrast demonstrated a well-circumscribed avidly enhancing mass in the right retroantral fat. On magnetic resonance imaging the lesion was homogenously slightly hyperintense to muscle on T1 weighted and T2 weighted images and enhanced avidly with contrast. Surgical resection was performed and pathology was consistent with solitary fibrous tumor. There have been very few reported cases of solitary fibrous tumors in the infratemporal fossa and none described as originating in the retroantral fat.






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