Question:

Which of the following answer choices is/are correct?
1. Colon descendens and sigmoid are the common sites of colon amyloidosis.
2. CT cannot differentiate amyloidosis from colitis.
3. Amyloid tumors can be detected in the small intestine.
4. Nodular mucosa is seen in colon amyloidosis.
5. CT is pathognomic for the diagnosis of amyloidosis.





Answer:

The correct answers for the question "Which of the following answer choices is/are correct?" are:

1. Colon descendens and sigmoid are the common sites of colon amyloidosis.

2. CT cannot differentiate amyloidosis from colitis.

3. Amyloid tumors can be detected in the small intestine.

4. Nodular mucosa is seen in colon amyloidosis.



Explanation

1. Amyloidosis affects most of all the descendens and rectosigmoid colon. (When the colon is affected, the descending and rectosigmoid colon are mostly involved.)

2. Colitis and amyloidosis cannot be distinguished by CT. (CT scan cannot reliably differentiate amyloid infestation from other causes of ischemic colitis or inflammatory bowel disease.)

3. Pseudotumoral formations are frequent in small bowel amyloidosis. (Other findings are jejunalization of the ileum, impaired motor activity, small polypoid protrusions, fine granular densities, and amyloid tumors.)

4. Thickened nodular mucosal folds are secondary to submucosal amyloid. (Barium enema shows luminal narrowing, loss of colonic haustrations, thickened mucosal folds, and a nodular mucosal pattern.)

5. Histopathology is of great importance in the diagnosis of amyloidosis. (The diagnosis of amyloidosis must be supported by histopathological examination as it has no pathognomic radiologic picture.)



From the manuscript:
Gastrointestinal amyloidosis presenting as enterocolitis on abdominal CT scan
Radiology Case. 2009 Oct; 3(10):11-14


This article belongs to the GI section.




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From the manuscript

Gastrointestinal amyloidosis presenting as enterocolitis on abdominal CT scan

Free full text article: Gastrointestinal amyloidosis presenting as enterocolitis on abdominal CT scan

Abstract
The imaging findings of amyloidosis are nonspecific and diverse due to its association with various chronic diseases such as multiple myeloma. We report a case of gastrointestinal amyloidosis presenting as enterocolitis on a contrast enhanced CT scan of the abdomen.






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