Question:

The best treatment of asymptomatic patient with established Extra-adrenal myelolipoma (EAML) is:
1. Resection
2. Hydroxyurea
3. Radiotherapy
4. Chemptherapy
5. Leave it alone





Answer:

The correct answer for the question "The best treatment of asymptomatic patient with established Extra-adrenal myelolipoma (EAML) is:" is:

5. Leave it alone



Explanation
1.    [Most surgical excisions were performed because of uncertainty of the tumor`s nature or because of mass effect]

2.    [Hydroxyurea increases the production of hemoglobin F] and is a line of treatment of extra-medullary hematopoiesis (EMH)

3.    [Irradiation of cord compression is advised] in cases of EMH.

4.    Chemotherapy is not indicated

5.    [Myelolipoma is an uncommon benign tumor. Fine needle biopsy is helpful in confirming the diagnosis in uncertain cases so that an asymptomatic patient will avoid unnecessary surgery]



From the manuscript:
Adrenal and Extra-adrenal Myelolipomas - A Comparative Case Report
Radiology Case. 2014 Jan; 8(1):1-12


This article belongs to the General section.




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From the manuscript

Adrenal and Extra-adrenal Myelolipomas - A Comparative Case Report

Free full text article: Adrenal and Extra-adrenal Myelolipomas -  A Comparative Case Report

Abstract
Myelolipoma is an uncommon benign tumour composed of mature fat tissue and haematopoietic elements and is most commonly found in the adrenal gland. We report a case, which was discovered incidentally on chest X-ray, of a rare occurrence of multifocal extra-adrenal myelolipoma in the thoracic paravertebral region. This was further investigated with multi-detector computed tomography and magnetic resonance imaging. The presumed diagnosis, of extra-adrenal myelolipoma, was histologically confirmed via tissue sample obtained by computed tomography guided biopsy. We compare the adrenal and extra-adrenal entities from the perspective of published literature and also review the cases, published in Pubmed, of extra-adrenal myelolipomas in order to summarize the different locations of this lesion.






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