Question:

All of the following are clinical findings suggestive of the presence of a phyllodes tumor EXCEPT:
1. breast mass that measures six centimeters in diameter
2. bulky breast mass diagnosed at age 37
3. Breast entirely replaced by a mass with thinning of the overlying skin
4. a new mass that has doubled in size over the past six months
5. 3 cm fixed mass with significant palpable ipsilateral axillary lymphadenopathy





Answer:

The correct answer for the question "All of the following are clinical findings suggestive of the presence of a phyllodes tumor EXCEPT:" is:

5. 3 cm fixed mass with significant palpable ipsilateral axillary lymphadenopathy



Explanation
1-4 are clinical findings that can suggest the presence of a phyllodes tumor.  Although choice 5 describes a young patient with a large palpable mass, the prominent axillary lymphadenopathy is not typical of a phyllodes tumor.  This case would most likely represent an adenocarcinoma [3-5].



From the manuscript:
Unusual Aggressive Breast Cancer: Metastatic Malignant Phyllodes Tumor
Radiology Case. 2013 Feb; 7(2):24-37


This article belongs to the Mamms section.




Bookmark and Share

From the manuscript

Unusual Aggressive Breast Cancer: Metastatic Malignant Phyllodes Tumor

Free full text article: Unusual Aggressive Breast Cancer:  Metastatic Malignant Phyllodes Tumor

Abstract
For the year of 2012, it has been estimated that breast cancer will account for the greatest number of newly diagnosed cancers and the second highest proportion of cancer related deaths among women. Breast cancer, while often lumped together as one disease, represents a diverse group of malignancies with different imaging findings, histological appearances and behavior. While most invasive primary breast cancers are epithelial derived adenocarcinomas, rare neoplasms such as the phyllodes tumor may arise from mesenchymal tissue. Compared to the breast adenocarcinoma, the phyllodes tumor tends to affect a younger population, follows a different clinical course, is associated with different imaging and histological findings and is managed distinctively. There may be difficulty in differentiating the phyllodes tumor from a large fibroadenoma, but the mammographer plays a key role in reviewing the clinical and imaging data in order to arrive at the correct diagnosis. Early diagnosis with proper surgical management can often cure non-metastatic phyllodes tumors. However, in rare cases where metastasis occurs, prognosis tends to be poor. This report describes the presentation, imaging findings and management of a metastatic malignant phyllodes tumor.






References



1. Siegel R, Naishadham D, Jemal A. Cancer statistics, 2012. CA Cancer J Clin 2012 Jan-Feb;62(1):10-29
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


2. Li CI, Uribe DJ, Daling JR. Clinical characteristics of different histologic types of breast cancer. Br J Cancer 2005 Oct 31;93(9):1046-1052
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


3. Suzuki-Uematsu S, Shiraishi K, Ito T, Adachi N, Inage Y, Taeda Y, Ueki H, Ohtani H. Malignant phyllodes tumor composed almost exclusively of a fibrosarcomatous component: a case report and review of malignant phyllodes tumors with metastases. Breast Cancer 2010 Jul;17(3):218-224
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


4. Confavreux C, Lurkin A, Mitton N, Blondet R, Saba C, Ranchère D, Sunyach MP, Thiesse P, Biron P, Blay JY, Ray-Coquard I. Sarcomas and malignant phyllodes tumours of the breast--a retrospective study. Eur J Cancer 2006 Nov;42(16):2715-2721
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


5. Chen WH, Cheng SP, Tzen CY, Yang TL, Jeng KS, Liu CL, Liu TP. Surgical treatment of phyllodes tumors of the breast: retrospective review of 172 cases. J SurgOncol 2005 Sep 1;91(3):185-194
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


6. Konstantakos AK, Graham DJ. Cystosarcoma phyllodes tumors in men. Am Surg 2003 Sep;69(9):808-811
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


7. Lee JW, Nadelman CM, Hirschowitz SL, Debruhl ND, Bassett LW. Malignant phyllodes tumor of a genotypic male, phenotypic female with liposarcomatous differentiation. Breast J 2007 May-Jun;13(3):312-313
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


8. Tan H, Zhang S, Liu H, Peng W, Li R, Gu Y, Wang X, Mao J, Shen X. Imaging findings in phyllodes tumors of the breast. Eur J Radiol 2012 Jan;81(1):e62-69
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


9. Bernardi G, Cavallaro G, Indinnimeo M, Fiore A, Basso L, D`Ermo G, De Toma G, Cavallaro A. Usefulness of ultrasounds in the management of breast phyllodes tumors. G Chir 2012 Mar;33(3):81-85
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


10. Harvey JA. Unusual breast cancers: useful clues to expanding the differential diagnosis. Radiology 2007 Mar;242(3):683-694
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine
11. Data on SEER (Surveillance, Epidemiology and End Results) Cancer statistics. National Cancer Institute. http://seer.cancer.gov/csr/1975_2009_pops09/results_single/sect_01_table.11_2pgs.pdf
Find similar topics on Find similar articles on Google scholarGoogle scholar :: Search for similar topics with the Radiology specific search engine Radiology search engine
Back Back



12. Parker SJ, Harries SA: Phyllodes tumours. Postgrad Med J 2001;77:428-435.
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


13. Liberman L, Bonaccio E, Hamele-Bena D, Abramson AF, Cohen MA, Dershaw DD. Benign and malignant phyllodes tumors: mammographic and sonographic findings. Radiology 1996 Jan;198(1):121-124
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


14. Gordon PB, Gagnon FA, Lanzkowsky L. Solid breast masses diagnosed as fibroadenoma at fine-needle aspiration biopsy: acceptable rates of growth at long-term follow-up. Radiology 2003 Oct;229(1):233-238
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


15. Adamietz BR, Kahmann L, Fasching PA, Schulz-Wendtland R, Uder M, Beckmann MW, Meier-Meitinger M. Differentiation between phyllodes tumor and fibroadenoma using real-time elastography. Ultraschall Med 2011 Dec;32 Suppl 2:E75-79
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


16. Nio Y, Iguchi C, Tsuboi K, Maruyama R. Ductal carcinoma in situ arising within a benign phyllodes tumor: A case report with a review of the literature. Oncol Lett 2011 Mar;2(2):223-228
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


17. Nomura M, Inoue Y, Fujita S, Sakao J, Hirota M, Souda S, Ohshima M. A case of noninvasive ductal carcinoma arising in malignant phyllodes tumor. Breast Cancer 2006;13(1):89-94
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


18. El Khouli RH, Louie A. Case of the season: a giant fibroadenoma in the guise of a phyllodes tumor; characterization role of MRI. Semin Roentgenol 2009 Apr;44(2):64-66
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


19. Foxcroft LM, Evans EB, Porter AJ. Difficulties in the pre-operative diagnosis of phyllodes tumours of the breast: a study of 84 cases. Breast 2007 Feb;16(1):27-37
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


20. Wurdinger S, Herzog AB, Fischer DR. AJR Am J. Roentgenol 185:1317-1321, 2005
Get full text
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


21. Schnitt, SJ. and Collins, LC. (2009) Fibroepithelial Lesions
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


22. Tavassoli, F.A., Devilee, P. (Eds): World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Breast and Female Genital Organs IARC Press: Lyon 2003.
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine


23. Tavassoli, F.A. (1992) Biphasic Tumors. In Pathology of the Breast, Second Edition Pages 598-611
Find similar topics on Read this article on PubMed :: Find similar articles on Google scholarScholar :: Search for similar topics with the Radiology specific search engine Radiology search engine




Search for articles with similar topics:

Keyword search:

1. phyllodes

2. cystosarcoma phyllodes

3. breast cancer

4. mesenchyal breast tumor

5. metastatic

6. enhancing septations


This article belongs to the Mamms section.


Search for more in the Internet

Peer-reviewed Radiology Search




Discuss it!

Bookmark and Share




© Journal of Radiology Case Reports - The Interactive Radiology Journal
Affiliated journal of Radiolopolis - The International Radiology Community


The Journal of Radiology Case Reports