Question:

Which of the following is associated with lymphocytic interstitial pneumonia?
1. Sjogren syndrome.
2. Patient with systemic disease.
3. Patient with connective tissue disorder.
4. Patient with acquired immunodeficiency syndrome.
5. All of the above.





Answer:

The correct answer for the question "Which of the following is associated with lymphocytic interstitial pneumonia?" is:

5. All of the above.



Explanation
A. Sjogren syndrome has been linked to lymphocytic interstitial pneumonia. [Conditions such as Sjogren syndrome, acquired immunodeficiency syndrome, Castleman syndrome and Epstein-Barr virus have been associated with LIP.]

B. Patients with underlying systemic disease are associated with lymphocytic interstitial pneumonia. [Conditions such as Sjogren syndrome, acquired immunodeficiency syndrome, Castleman syndrome and Epstein-Barr virus have been associated with LIP.]

C. Patients with connective tissue diseases have been associated with lymphocytic interstitial pneumonia. [Patients with LIP often have an underlying systemic disease or connective tissue disorder.]

D. Acquired immunodeficiency syndrome is associated with lymphocytic interstitial pneumonia. [Conditions such as Sjogren syndrome, acquired immunodeficiency syndrome, Castleman syndrome and Epstein-Barr virus have been associated with LIP.]

E. This is the best overall answer choice. [Lymphocytic interstitial pneumonia is associated with sjogren syndrome, patients` with systemic diseases, connective tissue disorders and acquired immunodeficiency syndrome.]



From the manuscript:
Reversed Halo Sign on CT as a Presentation of Lymphocytic Interstitial Pneumonia
Radiology Case. 2013 Oct; 7(10):51-56


This article belongs to the Chest section.




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From the manuscript

Reversed Halo Sign on CT as a Presentation of Lymphocytic Interstitial Pneumonia

Free full text article: Reversed Halo Sign on CT as a Presentation of Lymphocytic Interstitial Pneumonia

Abstract
A 52 year-old African American female with a past medical history of symptomatic uterine fibroids and increasing abdominal circumference underwent abdominal computed tomography (CT) as part of her workup. Because of an abnormality in the left lower lobe, CT of the chest was subsequently performed and showed a focal region of discontinuous crescentic consolidation with central ground glass opacification in the right lower lobe, suggestive of the reversed halo sign. The patient underwent percutaneous CT-guided core biopsy of the lesion, which demonstrated lymphocytic interstitial pneumonia, a benign lymphoproliferative disease characterized histologically by small lymphocytes and plasma cells. This case report describes the first histologically confirmed presentation of lymphocytic interstitial pneumonia with the reversed halo sign on CT.






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